⏳ Longevity & Anti-AgingPhase II

SS-31

Elamipretide · Bendavia · MTP-131

A mitochondria-targeting peptide for cellular energy and heart health

Typical Dose

0.1–0.5 mg/kg per day

Route

Subcutaneous

Frequency

Once daily

Cycle

Varies by protocol

SS-31 peptide hero image

Overview

SS-31 is a peptide designed to go directly inside your mitochondria — the energy-producing structures in your cells. Most compounds can't get in there. SS-31 can. Once inside, it protects a critical structure in the mitochondrial membrane that is responsible for producing most of your cellular energy. When mitochondria are damaged or aging, they produce less energy and more harmful byproducts. SS-31 helps fix that. It is being studied for heart failure, kidney disease, and general aging-related energy decline.

Key Benefits

Protects mitochondrial function
Reduces oxidative stress at the source
Supports cardiac function
May improve kidney function
Enhances cellular energy production
Neuroprotective effects

Mechanism of Action

Inside your mitochondria, there is a fatty molecule called cardiolipin that acts like the glue holding the energy-production machinery together. As we age or when cells are under stress, cardiolipin gets damaged, and the whole energy system becomes less efficient. SS-31 binds to cardiolipin and protects it. This reduces the production of harmful free radicals (the byproducts of energy production that damage cells) and keeps the energy-production chain running smoothly. The result is more energy output from each cell and less cellular damage over time.

Dosing Protocol

Typical Dose

0.1–0.5 mg/kg per day

Dose Range

Variable based on indication

Frequency

Once daily

Route

Subcutaneous injection or IV (in clinical settings)

Cycle Length

Varies by protocol

CLINICAL NOTES

Dosing is still being established. Consult with a healthcare provider for personalized guidance.

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Side Effects & Safety

Injection site reactions
Nausea (rare)
Generally well tolerated in studies

IMPORTANT DISCLAIMER

This information is for educational purposes only. Always consult a qualified healthcare provider before starting any peptide protocol. Individual responses vary and medical supervision is recommended.

Research References

Common Stacks

SS-31 is a mitochondria-targeted antioxidant. It works best alongside other longevity and energy peptides.

Frequently Asked Questions

Quick Reference

CategoryLongevity & Anti-Aging
Research StatusPhase II
Typical Dose0.1–0.5 mg/kg per day
RouteSubcutaneous
CycleVaries by protocol
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