Epitalon

Epithalon · Tetrapeptide · Ala-Glu-Asp-Gly

A telomere-lengthening peptide for cellular longevity

Typical Dose

5 mg once daily (standard cycle)

Route

Subcutaneous

Frequency

Once daily for 10–20 days per cycle

Cycle

10–20 days, 1–2 times per year

Overview

Epitalon is a tiny four-amino-acid peptide that has been studied for longevity for over 40 years, primarily by Russian scientists. It is based on a natural peptide produced by your pineal gland — a small gland in your brain that also controls your sleep-wake cycle. The big claim to fame for Epitalon is its ability to activate an enzyme called telomerase, which helps maintain the protective caps on your DNA. Those caps (telomeres) get shorter as you age, and shorter telomeres are linked to aging and disease.

Key Benefits

Activates telomerase enzyme to lengthen telomeres

Regulates the sleep-wake cycle via melatonin

Antioxidant properties

May extend lifespan (demonstrated in animal studies)

Supports immune function

Normalizes hormonal function

Mechanism of Action

Here is a helpful analogy: your chromosomes are like shoelaces, and telomeres are the plastic tips at the end that stop them from fraying. Every time a cell divides, those tips get a little shorter. Epitalon activates telomerase, the enzyme that rebuilds those tips. It also helps regulate melatonin production, which is why many users notice improved sleep quality alongside the longevity benefits.

Dosing Protocol

Typical Dose

5 mg once daily (standard cycle)

Dose Range

1–10 mg/day

Frequency

Once daily for 10–20 days per cycle

Route

Subcutaneous injection

Cycle Length

10–20 days, 1–2 times per year

CLINICAL NOTES

Standard dose is 5 mg once daily for 10–20 days. Lower doses of 1–5 mg are used for milder effects. Anti-aging protocols sometimes use up to 10 mg once daily. Treatment cycles are repeated 1–2 times per year with several months between cycles. Evening dosing is preferred due to its effects on melatonin.

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Reconstitution calculator and cycle planner pre-filled with Epitalon defaults

Reconstitution Guide

Vial Size

10 mg

BAC Water

1 mL (100 units)

Concentration

10 mg/mL

STEP-BY-STEP INSTRUCTIONS

Remove the caps from the bacteriostatic water (BAC water) and Epitalon vial and clean both stoppers with alcohol swabs. Draw 100 units (1 mL) of bacteriostatic water into a syringe and inject it gently into the Epitalon vial. Swirl gently until the peptide is fully dissolved — do not shake. The solution is now 10 mg/mL.

DRAW VOLUME REFERENCE

Dose	Units (U-100)	Volume (mL)
1 mg	10 units	0.10 mL
5 mg	50 units	0.50 mL
10 mg	100 units	1.00 mL

STORAGE

Lyophilized powder: store in a cool, dry, dark place for up to 1–2 years. Once reconstituted: refrigerate at 2–8°C and use within 20–30 days to maintain potency.

Side Effects & Safety

Generally very well tolerated

Mild fatigue (rare)

Injection site reactions

IMPORTANT DISCLAIMER

This information is for educational purposes only. Always consult a qualified healthcare provider before starting any peptide protocol. Individual responses vary and medical supervision is recommended.