Please read before exploring Peptide Insights
Important: The information on this website is intended for educational and research purposes only.
Peptide Insights provides information about peptides based on published scientific research and clinical literature. This content is designed to help you understand the science, not to guide personal medical decisions.
By continuing, you confirm that you are accessing this information for educational purposes and understand that it does not constitute medical advice.
Epithalon · Tetrapeptide · Ala-Glu-Asp-Gly
A telomere-lengthening peptide for cellular longevity
Typical Dose
5 mg once daily (standard cycle)
Route
Subcutaneous
Frequency
Once daily for 10–20 days per cycle
Cycle
10–20 days, 1–2 times per year
Epitalon is a tiny four-amino-acid peptide that has been studied for longevity for over 40 years, primarily by Russian scientists. It is based on a natural peptide produced by your pineal gland — a small gland in your brain that also controls your sleep-wake cycle. The big claim to fame for Epitalon is its ability to activate an enzyme called telomerase, which helps maintain the protective caps on your DNA. Those caps (telomeres) get shorter as you age, and shorter telomeres are linked to aging and disease.
Here is a helpful analogy: your chromosomes are like shoelaces, and telomeres are the plastic tips at the end that stop them from fraying. Every time a cell divides, those tips get a little shorter. Epitalon activates telomerase, the enzyme that rebuilds those tips. It also helps regulate melatonin production, which is why many users notice improved sleep quality alongside the longevity benefits.
Typical Dose
5 mg once daily (standard cycle)
Dose Range
1–10 mg/day
Frequency
Once daily for 10–20 days per cycle
Route
Subcutaneous injection
Cycle Length
10–20 days, 1–2 times per year
CLINICAL NOTES
Standard dose is 5 mg once daily for 10–20 days. Lower doses of 1–5 mg are used for milder effects. Anti-aging protocols sometimes use up to 10 mg once daily. Treatment cycles are repeated 1–2 times per year with several months between cycles. Evening dosing is preferred due to its effects on melatonin.
Vial Size
10 mg
BAC Water
1 mL (100 units)
Concentration
10 mg/mL
STEP-BY-STEP INSTRUCTIONS
Remove the caps from the bacteriostatic water (BAC water) and Epitalon vial and clean both stoppers with alcohol swabs. Draw 100 units (1 mL) of bacteriostatic water into a syringe and inject it gently into the Epitalon vial. Swirl gently until the peptide is fully dissolved — do not shake. The solution is now 10 mg/mL.
DRAW VOLUME REFERENCE
| Dose | Units (U-100) | Volume (mL) |
|---|---|---|
| 1 mg | 10 units | 0.10 mL |
| 5 mg | 50 units | 0.50 mL |
| 10 mg | 100 units | 1.00 mL |
STORAGE
Lyophilized powder: store in a cool, dry, dark place for up to 1–2 years. Once reconstituted: refrigerate at 2–8°C and use within 20–30 days to maintain potency.
IMPORTANT DISCLAIMER
This information is for educational purposes only. Always consult a qualified healthcare provider before starting any peptide protocol. Individual responses vary and medical supervision is recommended.
Epitalon is typically run in cycles for longevity. It pairs well with other anti-aging peptides.
Both target aging through different mechanisms — Epitalon via telomere support, GHK-Cu via collagen and epigenetic reset.
NAD+ + Epitalon is a popular longevity stack targeting cellular energy and telomere health simultaneously.
MOTS-c's mitochondrial benefits complement Epitalon's telomere support for a comprehensive longevity protocol.
Adding a GHRH to an Epitalon cycle supports GH levels alongside telomere health.
Real experiences from the Peptide Insights community
Have experience with Epitalon?
Log in to share your experience and help the community.
No reviews yet for Epitalon
Be the first to share your experience.