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Nicotinamide Adenine Dinucleotide · Beta-NAD+ · NAD
The master coenzyme for cellular energy, DNA repair, and sirtuin-driven longevity
Typical Dose
500 mg 2-3x weekly
Route
Subcutaneous
Frequency
2-3x weekly or daily
Cycle
Ongoing
Nicotinamide Adenine Dinucleotide (NAD+) is a coenzyme found in all living cells, essential for hundreds of metabolic reactions. It plays a central role in cellular energy production (ATP synthesis), DNA repair via PARP enzymes, and gene expression regulation via sirtuins (SIRT1-7). NAD+ levels decline significantly with age, and this decline is associated with metabolic dysfunction, neurodegeneration, and accelerated aging.
NAD+ serves as an electron carrier in redox reactions of cellular respiration. It is also a substrate for sirtuins (SIRT1-7), which are NAD+-dependent deacetylases that regulate gene expression, DNA repair, and metabolic adaptation. Declining NAD+ with age reduces sirtuin activity and impairs DNA repair capacity.
Typical Dose
500 mg 2-3x weekly
Dose Range
250-1000 mg per session
Frequency
2-3x weekly or daily
Route
Subcutaneous injection or IV infusion
Cycle Length
Ongoing
CLINICAL NOTES
IV infusion provides highest bioavailability. Administer slowly to minimize flushing. Can be combined with NMN or NR for synergistic effect.
IMPORTANT DISCLAIMER
This information is for educational purposes only. Always consult a qualified healthcare provider before starting any peptide protocol. Individual responses vary and medical supervision is recommended.
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