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Important: The information on this website is intended for educational and research purposes only.
Peptide Insights provides information about peptides based on published scientific research and clinical literature. This content is designed to help you understand the science, not to guide personal medical decisions.
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GHRP-1 Analog · Growth Hormone Secretagogue
A selective GH secretagogue with minimal side effects
Typical Dose
200–300 mcg per dose
Route
Subcutaneous
Frequency
1–3 times daily, ideally before bed
Cycle
8–12 weeks
Ipamorelin is often called the "cleanest" growth hormone peptide available, and for good reason. It triggers a pulse of growth hormone from your pituitary gland without significantly raising cortisol (the stress hormone) or prolactin (a hormone that can cause unwanted side effects). Think of it as a precise, targeted signal that says "release growth hormone now" without accidentally triggering other hormonal responses. It is most commonly paired with CJC-1295 for a powerful but well-tolerated combination.
Ipamorelin mimics ghrelin — the hormone your stomach releases when you are hungry, which also signals the pituitary to release growth hormone. By binding to the ghrelin receptor in the pituitary, Ipamorelin triggers a clean GH pulse. Unlike older growth hormone peptides (like GHRP-6), it is highly selective, meaning it only activates the growth hormone pathway and leaves cortisol and prolactin largely untouched. This selectivity is what makes it so popular for long-term use.
Typical Dose
200–300 mcg per dose
Dose Range
100–500 mcg per dose
Frequency
1–3 times daily, ideally before bed
Route
Subcutaneous injection
Cycle Length
8–12 weeks
CLINICAL NOTES
Best taken 30–60 minutes before bed to align with the natural nocturnal GH pulse. Avoid eating 2 hours before injection for best results.
IMPORTANT DISCLAIMER
This information is for educational purposes only. Always consult a qualified healthcare provider before starting any peptide protocol. Individual responses vary and medical supervision is recommended.
Ipamorelin is one of the cleanest GHRP peptides and pairs well with any GHRH for amplified GH release.
The most popular GH optimization stack. CJC-1295 (GHRH) + Ipamorelin (GHRP) produces synergistic, sustained GH pulses.
Sermorelin + Ipamorelin is a milder alternative to CJC-1295 stacks, popular for anti-aging protocols.
Adding BPC-157 to an Ipamorelin cycle accelerates recovery and tissue repair alongside GH optimization.
Tesamorelin + Ipamorelin amplifies GH release while targeting visceral fat.
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