CJC-1295 / Ipamorelin
CJC-1295 with DAC / Ipamorelin combo · GH Stack · GHRH/GHRP combo
The gold-standard GH secretagogue stack for physiological growth hormone release
Typical Dose
CJC-1295: 200 mcg + Ipamorelin: 200 mcg daily
Route
Subcutaneous
Frequency
Once or twice daily
Cycle
8-16 weeks
Overview
CJC-1295/Ipamorelin is one of the most popular peptide combinations in growth hormone research. CJC-1295 is a GHRH analog that stimulates the pituitary to produce GH, while Ipamorelin is a selective ghrelin receptor agonist that amplifies GH pulses without significantly raising cortisol or prolactin. Together, they produce a strong, physiological GH pulse that mimics the natural pulsatile release pattern.
Key Benefits
Mechanism of Action
CJC-1295 binds to GHRH receptors on pituitary somatotrophs, stimulating GH synthesis and release. Its drug affinity complex (DAC) extends its half-life to 6-8 days. Ipamorelin binds to the ghrelin receptor (GHS-R1a), amplifying the GH pulse. The combination produces synergistic GH release while maintaining the natural pulsatile pattern.
Dosing Protocol
Typical Dose
CJC-1295: 200 mcg + Ipamorelin: 200 mcg daily
Dose Range
100-300 mcg each per injection
Frequency
Once or twice daily
Route
Subcutaneous injection
Cycle Length
8-16 weeks
CLINICAL NOTES
Inject 30-60 minutes before sleep to align with natural GH pulse. Fast for 2 hours before injection. Cycle 5 days on, 2 days off.
Reconstitution calculator and cycle planner pre-filled with CJC-1295 / Ipamorelin defaults
Side Effects & Safety
IMPORTANT DISCLAIMER
This information is for educational purposes only. Always consult a qualified healthcare provider before starting any peptide protocol. Individual responses vary and medical supervision is recommended.
Research References
Common Stacks
This pre-made combination is already a complete GH stack. Adding recovery peptides is the most common complement.
Adding BPC-157 to a CJC/Ipamorelin cycle maximizes recovery and tissue repair alongside GH optimization.
TB-500 complements the GH-driven recovery of CJC/Ipamorelin with systemic healing support.
AOD-9604 adds targeted fat loss to the body composition benefits of GH optimization.
Frequently Asked Questions
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Related Peptides
Compounds often researched alongside CJC-1295 / Ipamorelin
CJC-1295
A long-acting GHRH analog for sustained growth hormone release
Ipamorelin
A selective GH secretagogue with minimal side effects
Sermorelin
The original GHRH analog for natural growth hormone optimization
Hexarelin
A potent GHRP with strong GH release and cardioprotective properties