🩹 Healing & RecoveryPreclinical

TB-500

Thymosin Beta-4 · Tβ4

Promotes systemic healing, flexibility, and cellular repair

Typical Dose

2–2.5 mg twice per week

Route

Subcutaneous

Frequency

Twice weekly (loading phase), then once weekly (maintenance)

Cycle

4–6 weeks loading, then maintenance

Overview

TB-500 is a synthetic version of a peptide your body already produces called Thymosin Beta-4. It is found in almost every cell in your body and plays a key role in how your cells move, multiply, and repair themselves. What makes TB-500 special is that its healing effects are systemic — meaning it works throughout your whole body, not just at one injury site. Athletes and researchers are particularly interested in it for recovery from chronic injuries and improving overall flexibility.

Key Benefits

Promotes systemic tissue healing throughout the body
Enhances flexibility and reduces muscle stiffness
Promotes new blood vessel growth
Reduces inflammation and oxidative stress
Supports cardiac tissue repair
May improve hair growth

Mechanism of Action

TB-500 works by increasing the availability of a protein called actin, which cells use to move and rebuild themselves. Think of actin as the scaffolding that cells climb to get to where they are needed. By boosting actin, TB-500 helps repair cells travel faster to injury sites, builds new blood vessels to improve circulation, and calms down the inflammatory signals that cause chronic pain and stiffness. While BPC-157 tends to work best at a specific injury site, TB-500 travels through your whole system.

Dosing Protocol

Typical Dose

2–2.5 mg twice per week

Dose Range

2–5 mg per week

Frequency

Twice weekly (loading phase), then once weekly (maintenance)

Route

Subcutaneous or intramuscular injection

Cycle Length

4–6 weeks loading, then maintenance

CLINICAL NOTES

Often stacked with BPC-157 for synergistic healing effects. The "Wolverine Stack" (BPC-157 + TB-500) is one of the most popular healing protocols.

Reconstitution calculator and cycle planner pre-filled with TB-500 defaults

Side Effects & Safety

Fatigue (temporary)
Head rush or lightheadedness
Injection site reactions
Potential tumor growth concerns (theoretical, not confirmed in humans)

IMPORTANT DISCLAIMER

This information is for educational purposes only. Always consult a qualified healthcare provider before starting any peptide protocol. Individual responses vary and medical supervision is recommended.

Research References

Common Stacks

TB-500 (Thymosin Beta-4) is almost always run alongside BPC-157 for a synergistic healing protocol.

Frequently Asked Questions

Quick Reference

CategoryHealing & Recovery
Research StatusPreclinical
Typical Dose2–2.5 mg twice per week
RouteSubcutaneous
Cycle4–6 weeks loading, then maintenance

Community Reviews

Real experiences from the Peptide Insights community

Have experience with TB-500?

Log in to share your experience and help the community.

Log In to Review

No reviews yet for TB-500

Be the first to share your experience.