Wolverine Stack
BPC-157 + TB-500 · The Healing Stack
The most popular healing peptide combination — synergistic local and systemic repair
Typical Dose
1 mg once daily (Weeks 1–4)
Route
Subcutaneous
Frequency
Once daily; every other day for maintenance
Cycle
8+ weeks with maintenance phase
Overview
The Wolverine Stack combines BPC-157 and TB-500 into a single protocol that addresses both localized and systemic healing simultaneously. Named after the Marvel character known for rapid regeneration, this combination is considered the gold standard healing protocol in the peptide community. BPC-157 handles targeted, localized repair while TB-500 provides systemic anti-inflammatory and healing support throughout the body.
Key Benefits
Mechanism of Action
BPC-157 upregulates growth hormone receptors in tendon fibroblasts and promotes angiogenesis through VEGF, providing targeted healing at the injury site. TB-500 upregulates actin expression throughout the body, promoting cell migration and systemic tissue repair while reducing inflammation via cytokine modulation. Together, they address healing from both a local and systemic perspective simultaneously.
Dosing Protocol
Typical Dose
1 mg once daily (Weeks 1–4)
Dose Range
1–2 mg/day
Frequency
Once daily; every other day for maintenance
Route
Subcutaneous injection (abdomen or near injury site)
Cycle Length
8+ weeks with maintenance phase
CLINICAL NOTES
Titration schedule: Weeks 1–4: inject 1 mg (1,000 mcg) once daily. Weeks 5–8: increase to 2 mg (2,000 mcg) daily if additional benefit is needed. Maintenance (beyond Week 8): inject 1–2 mg every other day as needed for continued healing support. Inject near the injury site for best localized effect.
Reconstitution Guide
Vial Size
40 mg (BPC-157 20mg + TB-500 20mg)
BAC Water
4 mL (400 units)
Concentration
5 mg/mL of each compound
STEP-BY-STEP INSTRUCTIONS
Pop off the caps on the bacteriostatic water and the peptide vial, then wipe with alcohol prep pads. Draw 4 mL (400 units) of bacteriostatic water and inject it into the vial containing the combined 20 mg BPC-157 + 20 mg TB-500 powder. The solution is now 5 mg/mL of each compound.
DRAW VOLUME REFERENCE
| Dose | Units (U-100) | Volume (mL) |
|---|---|---|
| 500 mcg | 10 units | 0.10 mL |
| 1 mg | 20 units | 0.20 mL |
| 2 mg | 40 units | 0.40 mL |
STORAGE
Once reconstituted: store vial in the refrigerator (36–46°F / 2–8°C) and use within 30–60 days for best potency.
Side Effects & Safety
IMPORTANT DISCLAIMER
This information is for educational purposes only. Always consult a qualified healthcare provider before starting any peptide protocol. Individual responses vary and medical supervision is recommended.
Research References
Frequently Asked Questions
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Related Peptides
Compounds often researched alongside Wolverine Stack
BPC-157
The most studied healing peptide for tissue repair and gut health
TB-500
Promotes systemic healing, flexibility, and cellular repair
Pentadeca Arginate
An arginine-enhanced BPC-157 analog studied for enhanced bioavailability and tissue repair
GLOW Peptide Blend
A 3-peptide anti-aging blend combining GHK-Cu, BPC-157, and TB-500 to boost collagen, repair tissue, and improve skin, hair, and energy.