💪 Muscle Growth & PerformancePreclinical

Follistatin-344

FST-344 · Follistatin

A myostatin inhibitor that dramatically increases muscle growth potential

Typical Dose

100 mcg per day

Route

Intramuscular

Frequency

Once daily

Cycle

10–30 days (short cycles recommended)

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Overview

Follistatin-344 is a naturally occurring glycoprotein that acts as a potent inhibitor of myostatin, the protein that limits muscle growth. By blocking myostatin, Follistatin-344 can dramatically increase muscle mass and strength. It is one of the most discussed peptides in the performance enhancement community due to its remarkable muscle-building potential.

Key Benefits

Inhibits myostatin, removing the natural limit on muscle growth
Dramatically increases muscle mass and strength
Promotes satellite cell activation for muscle repair
May improve endurance and athletic performance
Potential therapeutic use for muscular dystrophy
Reduces body fat through increased muscle mass

Mechanism of Action

Follistatin-344 binds to and neutralizes myostatin (GDF-8), a TGF-beta family member that inhibits muscle cell growth and differentiation. By blocking myostatin, Follistatin allows muscle satellite cells to proliferate and differentiate without restriction. It also inhibits activin, another muscle growth inhibitor, providing a dual mechanism for enhanced muscle development.

Dosing Protocol

Typical Dose

100 mcg per day

Dose Range

50–200 mcg per day

Frequency

Once daily

Route

Intramuscular injection (into target muscle)

Cycle Length

10–30 days (short cycles recommended)

CLINICAL NOTES

Intramuscular injection into the target muscle is the standard protocol. Short cycles (10–30 days) are recommended due to the potency and limited long-term safety data. The muscle-building effects can be dramatic and relatively permanent. Extremely limited human safety data available.

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Side Effects & Safety

Potential for disproportionate muscle growth
Tendon stress from rapid muscle growth
Limited long-term safety data
Potential cardiovascular effects with extreme muscle mass gains

IMPORTANT DISCLAIMER

This information is for educational purposes only. Always consult a qualified healthcare provider before starting any peptide protocol. Individual responses vary and medical supervision is recommended.

Research References

Common Stacks

Follistatin-344 inhibits myostatin for muscle growth. It pairs well with anabolic and recovery peptides.

Frequently Asked Questions

Quick Reference

CategoryMuscle Growth & Performance
Research StatusPreclinical
Typical Dose100 mcg per day
RouteIntramuscular
Cycle10–30 days (short cycles recommended)
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