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Peptide Insights provides information about peptides based on published scientific research and clinical literature. This content is designed to help you understand the science, not to guide personal medical decisions.
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ACTH 4-7 Pro8-Gly9-Pro10 · Heptapeptide
A neuropeptide for enhanced focus, memory, and brain protection
Typical Dose
500 mcg–1 mg once daily
Route
Subcutaneous
Frequency
Once daily
Cycle
2–4 weeks on, 1–2 weeks off
Semax is a brain-boosting peptide that has been used as a prescription medicine in Russia for decades. It was developed from a piece of a hormone your body already makes, and it works by increasing a protein in your brain called BDNF — often nicknamed "brain fertilizer" because it helps neurons grow, connect, and survive. People use it for sharper focus, better memory, and protection against cognitive decline. It is also used clinically in Russia for stroke recovery and brain injuries.
Semax works by increasing BDNF (Brain-Derived Neurotrophic Factor), a protein that acts like fertilizer for your neurons. More BDNF means your brain cells grow stronger connections, survive longer, and recover better from damage. Semax also nudges your dopamine and serotonin systems, which is why users often report improved mood and motivation alongside the cognitive benefits. When taken as a nasal spray, it travels directly from your nose to your brain, which is why effects can be felt within 30 to 60 minutes.
Typical Dose
500 mcg–1 mg once daily
Dose Range
500 mcg–2 mg/day
Frequency
Once daily
Route
Subcutaneous injection
Cycle Length
2–4 weeks on, 1–2 weeks off
CLINICAL NOTES
Common dosing ranges from 500 mcg to 1 mg per day. Dosage may vary based on individual goals, tolerance, and clinical guidance.
Vial Size
10 mg
BAC Water
1 mL (100 units)
Concentration
10 mg/mL
STEP-BY-STEP INSTRUCTIONS
Remove the caps from the bacteriostatic water (BAC water) and Semax vial and clean both stoppers with alcohol swabs. Draw 100 units (1 mL) of bacteriostatic water into a syringe and inject it into the Semax vial. Swirl gently until fully dissolved — do not shake. The solution is now 10 mg/mL.
DRAW VOLUME REFERENCE
| Dose | Units (U-100) | Volume (mL) |
|---|---|---|
| 500 mcg | 5 units | 0.05 mL |
| 1 mg | 10 units | 0.10 mL |
| 2 mg | 20 units | 0.20 mL |
STORAGE
Lyophilized powder: store in a cool, dry place. Once reconstituted: refrigerate and use within 30 days.
IMPORTANT DISCLAIMER
This information is for educational purposes only. Always consult a qualified healthcare provider before starting any peptide protocol. Individual responses vary and medical supervision is recommended.
Semax is a cognitive enhancer that pairs well with anxiolytic peptides for a balanced nootropic stack.
Semax (stimulating/focus) + Selank (calming/anxiolytic) is the classic balanced nootropic stack.
Pinealon adds neuroprotective and sleep-quality benefits to Semax's cognitive enhancement.
Methylene blue amplifies Semax's cognitive effects through mitochondrial support.
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