Pinealon

EDR Peptide · Glu-Asp-Arg

A pineal gland peptide for neuroprotection and sleep optimization

Typical Dose

5–10 mg per day

Route

Subcutaneous

Frequency

Once daily, in the evening

Cycle

10 days, 2–3 times per year

Overview

Pinealon is a three-amino-acid peptide derived from the pineal gland — the same gland that produces melatonin and regulates your sleep cycle. It is studied primarily for protecting the brain from aging and oxidative damage, and for improving sleep quality. It is often paired with Epitalon as part of a longevity protocol focused on the pineal gland. While the research is still early, it is particularly interesting for people concerned about cognitive decline as they age.

Key Benefits

Neuroprotective against oxidative stress

Improves sleep quality

May slow cognitive decline

Antioxidant properties

Supports pineal gland function

Mechanism of Action

Pinealon can cross the blood-brain barrier — the protective filter that keeps most substances out of the brain. Once inside, it interacts directly with the DNA in neurons, switching on genes that protect brain cells from damage and aging. It also supports the pineal gland's ability to produce melatonin, which is why evening dosing is recommended. Better melatonin production means better sleep, and better sleep is one of the most powerful things you can do for long-term brain health.

Dosing Protocol

Typical Dose

5–10 mg per day

Dose Range

5–20 mg/day

Frequency

Once daily, in the evening

Route

Subcutaneous injection or intranasal

Cycle Length

10 days, 2–3 times per year

CLINICAL NOTES

Evening dosing is recommended due to its effects on sleep and melatonin. Often used in combination with Epitalon.

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Reconstitution calculator and cycle planner pre-filled with Pinealon defaults

Side Effects & Safety

Drowsiness (take in evening)

Generally very well tolerated

IMPORTANT DISCLAIMER

This information is for educational purposes only. Always consult a qualified healthcare provider before starting any peptide protocol. Individual responses vary and medical supervision is recommended.