MT-2 · Melanotan 2
A melanocortin peptide that promotes tanning, libido, and sexual function
Typical Dose
0.5–1 mg per dose
Route
Subcutaneous
Frequency
Daily during loading phase, then as needed
Cycle
2–4 weeks loading, then maintenance as needed
Melanotan II started as a sunless tanning project and ended up being one of the most talked-about peptides in the biohacking world. It is a synthetic version of a hormone your body naturally produces to control skin pigmentation. Researchers discovered it had powerful effects on sexual arousal and libido as a side effect — which ended up being more interesting to many users than the tanning. It also suppresses appetite. It is one of the more potent peptides on this site and comes with a meaningful side effect profile, so it requires careful consideration.
Melanotan II activates a family of receptors called melanocortin receptors, which are found throughout your body. Different receptors do different things. The ones in your skin cells (MC1R) respond by producing more melanin — the pigment that makes skin darker. The ones in your brain (MC3R and MC4R) control sexual arousal and appetite. By activating all of these at once, Melanotan II produces tanning, increased libido, and appetite suppression simultaneously. This broad activation is also why the side effect profile is more significant than more targeted peptides.
Typical Dose
0.5–1 mg per dose
Dose Range
0.25–2 mg per dose
Frequency
Daily during loading phase, then as needed
Route
Subcutaneous injection
Cycle Length
2–4 weeks loading, then maintenance as needed
CLINICAL NOTES
Start with a very low dose (0.25 mg) to assess tolerance due to nausea. Administer in the evening to minimize side effects. Tanning effects require some UV exposure to activate. Not recommended for individuals with a history of melanoma.
IMPORTANT DISCLAIMER
This information is for educational purposes only. Always consult a qualified healthcare provider before starting any peptide protocol. Individual responses vary and medical supervision is recommended.
Melanotan II affects pigmentation, libido, and appetite. It can be combined with sexual health peptides.
Real experiences from the Peptide Insights community
Have experience with Melanotan II?
Log in to share your experience and help the community.
No reviews yet for Melanotan II
Be the first to share your experience.